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18,19 When wild-kind mice are administered a artificial cannabinoid, There's an predicted lower in GABA synaptic transmission, when CB1 receptor knockout mice don't have any decrease in GABA synaptic transmission. Curiously, there is a lower in the level of glutamate synaptic transmission in both equally wild-style and CB1-receptor knockout mice. T
18,19 When wild-form mice are administered a synthetic cannabinoid, There exists an predicted reduce in GABA synaptic transmission, whilst CB1 receptor knockout mice don't have any lessen in GABA synaptic transmission. Curiously, You will find a minimize in the extent of glutamate synaptic transmission in the two wild-kind and CB1-receptor knockout